Last year OU scored 85pt/gm and gave up 82pt/gm. Trae, Lattin, McGusty, & Shepherd accounted for roughly 68 points with points and assists.
So let's say OU gives up 72 points a game this year after losing their 2 worst defenders and emphasizing defense. So they have to account for about 58 points to have a similar season. (I know a lot more goes into this)
Calixte - 20 points
Reynolds - 14 points
Bienemy - 10 points
Kuath - 3 points
Doolittle - 8 points (added)
James - 5 points (added)
McNease - 5 points (added)
Manek - 5 points (added)
Odomes- 2 points (added)
That totals up to 72 points added so even if I overshot you still have room to work with.