March Madness and Covid-19

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SoonerJK12 said:
You are not understanding the problems with a RETROSPECTIVE COHORT STUDY. There is so much selection bias and observational bias in a study like that. Especially when studying a drug like this during a pandemic. And we don't even know if the two cohort were similar because they haven't released any Table 1 data.

My point was that study should not even be a data point in your analysis. It's even worse than the French study -- which to your point was not rigorous. You aren't gonna find an answer to the question "Does hydroxychloroquine benefit COVID patients" with a retrospective chart review. You should stop commenting about the effectiveness of the drug until a controlled trial plays out.

You keep screaming for evidence and then using terrible evidence in your arguments. That's all I am saying.
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You know what? Fair enough, we can revisit this topic at least when this study has been peer-reviewed and formally published (or not published). I will gladly eat my crow if it's debunked.
 
From Cuomo press conference today. Analysis of their antibody tests they conducted to find out infection rate:

- 13% of state likely infected
- 20% of NYC

That makes so much sense since the deaths so much higher there. Death rate is 0.5% based on their numbers per Cuomo.
 
At the height of hospitalizations 560 Oklahomans were seeking treatment at these facilities. Today the number stands at 284.
 
SoonerJK12 said:
From Cuomo press conference today. Analysis of their antibody tests they conducted to find out infection rate:

- 13% of state likely infected
- 20% of NYC

That makes so much sense since the deaths so much higher there. Death rate is 0.5% based on their numbers per Cuomo.
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I was really hoping those numbers would be higher. Seems realistic, though.
 
steverocks35 said:
https://apnews.com/a5077c7227b8eb8b0dc23423c0bbe2b2

Looks like my skepticism was correct. Barring some wild error in this preliminary study, this pretty much puts the nail in the coffin of hydroxychloroquine. It was foolish to put so many resources into this unproven drug. We should have been focused on antivirals.
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I originally skipped past this link as I assumed it was to the RCT I vaguely alluded to a few posts earlier. In general, retrospective analysis are considered slightly better than nothing, but in a lot of cases, nothing is actually better. There is a huge bias, as the sicker patient tends to get more aggressive treatments -- which means those with aggressive treatments will have worse outcomes simply because they were sicker to begin with. In these situations, you need controlled studies. We do have an RCT out of China that suggest plaquenil is ineffective, thought it would be premature to say it's the final nail in the coffin given that it's small and preprint at this time.

https://www.medrxiv.org/content/10.1101/2020.04.10.20060558v1.article-info
 
Eielson said:
I originally skipped past this link as I assumed it was to the RCT I vaguely alluded to a few posts earlier. In general, retrospective analysis are considered slightly better than nothing, but in a lot of cases, nothing is actually better. There is a huge bias, as the sicker patient tends to get more aggressive treatments -- which means those with aggressive treatments will have worse outcomes simply because they were sicker to begin with. In these situations, you need controlled studies. We do have an RCT out of China that suggest plaquenil is ineffective, thought it would be premature to say it's the final nail in the coffin given that it's small and preprint at this time.

https://www.medrxiv.org/content/10.1101/2020.04.10.20060558v1.article-info
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These are all good points. I am aware of the potential bias in these kinds of surveys and I assumed (maybe wrongly) that the researchers were also aware of the potential biases and adjusted the instrument accordingly. Some of these biases can be somewhat overcome with large enough sample sizes, so that you are comparing apples to apples, at least mostly. You are correct though, nothing can take the place of a well-executed RCT. You are also correct that this is a pre-print, which is why I am going to wait for peer-review and publication (if it gets published). Thanks for your insight.
 
I hope Oklahoma is doing a better job in reporting ChiCom infections and deaths. PA is having a hard time getting accurate numbers.

Coroners here are saying The PA Department of Health is doing a poor job of communicating with them, resulting in inaccurate numbers of deaths and cases involving Wuhan. Of course, PA, like many other states I have read, are inflating numbers of both. The DoH had to walk back hundreds of deaths attributed to Covid.

“There’s a discrepancy in the numbers,” Charles E. Kiessling Jr., president of the Pennsylvania Coroners Association and coroner in Lycoming County, said Thursday. “I’m not saying there’s something going on.... I’m not a conspiracy theory guy. But accuracy is important.”

https://www.inquirer.com/health/cor...t-changes-confusion-coroanvirus-20200423.html

P.S. Yes, that's really the PA Secretary of Health Rachel Levine, formerly known as Richard. Be nice, and no picking on me. I'm sensitive.

You should see our LT Governor. He looks like an outlaw biker.
 
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Broken Arrow, OK is fully open for business. Did a quick drive around and everything looks like its back open.

Now we wait and see what happens.
 
steverocks35 said:
Ah I get it, you're just being racist. It's not a flu, it's called SARS-CoV-2 and the disease is known as Covid-19. Also, Rush said this is the "19th Coronavirus" so you might want to find a better source of information.
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Racist, umm, no. Realist, yes. Rush has called it all sorts of names. Maybe you should listen more often.
 
paboomersooner said:
Racist, umm, no. Realist, yes. Rush has called it all sorts of names. Maybe you should listen more often.
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If you want anyone to take you seriously you will call the disease by the correct name, not some childish racist nonsense you heard on a grifting shock-jock's radio show.
 
steverocks35 said:
If you want anyone to take you seriously you will call the disease by the correct name, not some childish racist nonsense you heard on a grifting shock-jock's radio show.
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You can take me as serious or not as you want to. I sleep well at night either way. I'm just shocked you focused more on the geographical terms I use as opposed to the more pertinant information in the article.

I use some of the terms I use to "catch" SJW'S. Caught one!

Oh. Almost forgot. I've been called worse by better.

Good day sir.
 
paboomersooner said:
You can take me as serious or not as you want to. I sleep well at night either way. I'm just shocked you focused more on the geographical terms I use as opposed to the more pertinant information in the article.

I use some of the terms I use to "catch" SJW'S. Caught one!

Oh. Almost forgot. I've been called worse by better.

Good day sir.
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I read the article, there's some reporting confusion as the death toll mounts, shocking!

Also, it's spelled "pertinent."
 
steverocks35 said:
I read the article, there's some reporting confusion as the death toll mounts, shocking!

Also, it's spelled "pertinent."
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And here come the Spellcheck police. Or should I have put a space between spell and check? NVM. Your smart enough to figure it out.
 
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